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Periodontitis is a chronic bacterial infection caused by microbial plaque often known as gum disease that is colonized on tooth surface and below the gingival margin. It involves progressive loss of the alveolar bone, which is a thickened ridge of bone that contains tooth socket over the bones that holds teeth. According to National Institutes of Health 2017, around 20-15% of global population is estimated to suffer from severe periodontitis in comparison to 5-10% in 2004, which is propelling demand for its diagnosis and treatment worldwide in the medical industry.

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In periodontitis, gums are pulled away from teeth and form spaces (pockets), which are prone to get infected. If such infection is untreated, it can lead to increase periodontal pocket length and bleeding on probe, in turn leading to the alveolar bone loss and teeth loss. In order to complement a non-surgical therapy in periodontitis multiple antimicrobial options are available, such as metronidazole, chlorhexidine, minocycline, doxycycline, tetracycline, which can be locally delivered to mucosa. These drugs are used to inhibit periodontopathogenic microorganism as well as modulate the inflammatory response of tissues. Oral care and dental hygiene are one of the major concerns worldwide. High prevalence of periodontal disease is propelling demand for oral treatment. Periodontal disease is a result of various risk factors, such as aging, smoking, poor oral hygiene, heredity, stress, and other medical conditions.

Periodontal disease are majorly observed in adults. According to the Centre for Disease Control and Prevention (CDC), in 2018, the prevalence of periodontitis has been estimated to be over 50% in U.S. adults aged 30 years and older i.e. 64.7 million Americans. Among those adults, 8.7% showed mild disease, 30% demonstrated moderate disease, 8.5% had severe chronic periodontitis. Disease prevalence increases with age, with 70% adults, who are 65 years and above, suffering from periodontitis. There are many environmental risk factors that are associated with inflammatory responses, which include smoking, diabetes mellitus, and poor health habits driving the chronic inflammatory response in periodontitis, and are beneficial for the periodontitis disease therapeutic market.

Local antibiotics for the treatment of periodontal disease to present more growth opportunities in the periodontal disease therapeutics market. Increasing preference for controlled local drug delivery approaches over systemic drug delivery due to better therapeutic outcomes by achieving factors such as site specific delivery, low dose requirement, reduces side effects favors the growth of local antibiotics. Furthermore, it provide safe and effective mode of treatment and is expected to lead the market in the next few years due to various advantages. Systemic antibiotics is expected to hold dominance in global market due to factors such as product affordability, availability, and high market penetration. Growing number of preventive care for dental and gum problems and poor reimbursement policies in many economies are hindering the growth of periodontal disease therapeutic market.

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Based on geography, North America dominated the periodontal disease therapeutics market due to high awareness of periodontal disease. High prevalence of periodontal disease due to desk bound or seated lifestyle, efficient reimbursements, and drug abuse. Also, increased healthcare spending has contributed to growth of market. For instance, in the U.S., according to the Centers for Medicare and Medicaid Services (CMS) spending for dental services increased by 4.6% in 2016, to US $124.4 Bn, a slight acceleration from 4.4% in growth in 2015. Furthermore, Asia Pacific is expected as an emerging lucrative market for periodontal therapeutics market due to large patient pool, growing healthcare infrastructure, and expenditure. Also, investments into research and development for more effective therapies by prominent players in the region drives the periodontal disease therapeutics market.

Key Vendors:

DenMat Holdings LLC., 3M, Valeant Pharmaceuticals International, Inc., Galderma S.A., Dexcel Pharma Ltd., Kaken Pharmaceutical Co., Ltd., and OraPharma Inc.

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Respiratory Syncytial Virus (RSV) is responsible for many chronic conditions such as pneumonia, bronchitis, asthma, and respiratory disease. It primarily affects neonates, infants and adults and is responsible for outpatient visits, hospitalization and death in some cases. Therefore, diagnosis of  RSV- associated diseases is crucial to avoid further medical severity. Symptoms of RSV presence include, rhinorrhea, cough, wheeze, respiratory distress, and hypoxemia. Molecular diagnostic is most widely used techniques for diagnosing RSV.

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High prevalence of respiratory infections due to RSV is a major factor driving growth of the respiratory syncytial virus diagnostics market. According to a report by the Lancet, 2017, around 33·1 million episodes of RSV induced acute lower respiratory infections that resulted in around 3·2 million hospitalizations and around 59,600 in-hospital deaths in children younger than 5 years of age, worldwide, in 2015. Moreover, the report stated that the overall RSV- acute lower respiratory infections- related mortality was around 118200 in 2015.

Furthermore, high prevalence of several chronic conditions such as pneumonia and other respiratory tract infections due to RSV is a major factor contributing to growth of the market over the forecast period. For instance, according to a report by World Health Organization (WHO), May 2018, chronic obstructive pulmonary disease (COPD) and lower respiratory tract infection are amongst top five chronic diseases with highest mortality rate, worldwide. The report stated that around 3 million each deaths were registered due to COPD and lower respiratory tract infection in 2016, worldwide.

On the basis of Geography, respiratory syncytial virus diagnostics market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to be dominant in the respiratory syncytial virus diagnostics market over the forecast period.

According to study published in journal American Family Physician in 2017, around 2% to 3% of infants, younger than 12 months are hospitalized with an RSV infection, annually, in the U.S. As per same source, Around 57,500 hospitalizations and 2.1 million outpatient visits are associated with RSV infections in children younger than five years, annually, in the U.S. It can be concluded from epidemiological data that the U.S. has high potential for respiratory syncytial virus diagnostics market. Presence of key players and their products in North America would be another important driver for the market growth.

Asia Pacific and Latin America would witness highest CAGR in respiratory syncytial virus diagnostics market. According to study published in the Lancet in September 2017, lower middle income countries witnessed around 43,600 deaths due to RSV-ALRI whereas upper middle income countries witnessed around 17900 deaths, in 2015. Furthermore, children in this region often do not receive adequate vaccination, which leads to frequent infection incidences from variety of diseases including RSV. According to World Health Organization (WHO) 2018, worldwide, around 86% of infants are vaccinated against 26 diseases. However, around 19.5 million children remain unvaccinated that leads to around 2-3 million deaths, annually, of which around 90% belong to low and middle income countries.

WHO is running the pilot projects of vaccination in countries of developing regions such Latin America, Africa, and Asia Pacific to achieve100% detection of the RSV infections amongst infants, neonates and children under five years of age.This is expected to reduce the mortality rate  and hospitalization from RSV associated acute lower respiratory infections (ALRI). It would also establish RSV diagnostic centers over the forecast period in these regions.

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Key Vendors:

F. Hoffmann La-Roche AG , Becton, Dickinson and Company, Novartis AG, Abbott Laboratories, Ortho Clinical Diagnostics, Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., BioMerieux, DiaSorin SPA, Millipore-sigma, Quidel Corporation, Alere Inc., Coris BioConcept, Fast-track Diagnostics, and Quest Diagnostics.

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Chronic lymphocytic leukemia (CLL) is a most common type of leukemia found in adults. It is a kind of malignancy characterized by production of abnormal white blood cells in the bone marrow. Symptoms include, swelling of the lymph nodes, fatigue, fever, infection, pain beneath the ribs, and weight loss. Although CLL is rarely seen in children and people under age 40, it is more prevalent in geriatric population. Moreover, causes of CLL are largely unknown and it is more severe than acute leukemia. The prevalence of CLL is high in males than females. Although, the incidence of this disorder is higher in white population than Asian populations, the precise cause for this cannot be explained.

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The diagnosis of CLL includes Blood Cell Count and Examination, Bone Marrow Examination for patients followed by treatment. The treatment includes single or combination drug therapy, targeted therapies, monoclonal antibody therapies, white blood cell (neutrophil) growth factors. In addition to this, there are radiation therapy and splenectomy which are rarely used for the treatment.

High prevalence of CLL coupled with its high mortality rate, demonstrates the unmet market need for better therapeutics. According to the American Cancer Society (ACS) estimates, around 20,110 new cases of chronic lymphocytic leukemia and 4,660 deaths from CLL is expected in year 2017 in U.S. Furthermore, high prevalence of CLL in geriatric population is expected to increase demand for chronic lymphocytic leukemia therapeutics. According to the United Nations data, in 2015, around 901 million people in the world were over 60 years of age and this number is expected to reach 1.4 billion by 2030 and to 2.1 billion by 2050.

Furthermore, increasing number of incidences of comorbidities, especially among geriatric population and launch of new pipeline drugs are major factors contributing to growth of the chronic lymphocytic leukemia therapeutics market. For instance, on December 8, 2015, Bendeka injection—manufactured under the collaboration of Teva Pharmaceuticals Industries Ltd. and Eagle Pharmaceuticals Inc. acquired approval from FDA for the treatment of patients with CLL and indolent B-cell non-Hodgkin lymphoma (NHL) — progressed during or within six months of treatment with rituximab or a rituximab-containing regimen.

On the basis of region, the chronic lymphocytic leukemia therapeutics market is segmented into North America, Europe, Latin America, Asia Pacific, Middle East, and Africa. North America accounted for the largest market share in 2016 due to the presence of breakthrough pipeline drugs. For instance, the drug Acalabrutinib—manufactured by Acerta Pharma BV—is under phase 2 clinical trial for the treatment of CLL and small lymphocytic lymphoma (SLL) and the study is expected to complete in January 2019

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Key Vendors:

F. Hoffmann-La Roche Ltd, Novartis International AG, GlaxoSmithKline Pharmaceuticals Limited, Celgene Corporation, Genmab A/S, Abbvie Inc. Teva Pharmaceutical Industries Ltd., Biogen Idec, AstraZeneca plc, Arno Therapeutics, Genzyme Corporation, Gilead Sciences INC., and others.

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H1N1 influenza virus causes viral disease, commonly known as swine flu, which mostly affects the respiratory system. Swine flu is characterized by infection from H1N1 strain. Symptoms of H1N1 flu are fever, cough, sore throat, runny or stuffy nose, watery and red eyes, body aches, headache, fatigue, and diarrhea. H1N1 spreads through contact with contaminated air or geographical locations infected with virus. H1N1 infection may worsen other chronic respiratory conditions such as bronchitis, pneumonia, COPD, and sometimes even death due to respiratory failure.

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H1N1 vaccine is an important innovation to tackle the H1N1 pandemic since 2009. Initially, the vaccines developed or available were inactivated monovalent vaccines that could prevent infection from most of the strains of H1N1. There are two routes of administration such as intradermal for inactivated vaccine and intranasal for live attenuated vaccine. Both routes shown efficacy profile and are bioequivalent against preventing H1N1 infection. Global H1N1 vaccine market has presence of both multinational pharmaceutical companies and companies from emerging economies.

One of the major factor propelling growth of H1N1 market is increased incidence of disease and episodes of pandemic worldwide from H1N1 infection. According to World Health Organization’s (WHO) 2018, factsheet estimates, 290,000 to 650,000 deaths are reported each year from all types of influenza infection (including Influenza A i.e. H1N1). Each year there are 3 to 5 million cases of severe illness from viral influenza infection globally, according to the same source.

Government initiatives, both internationally and nationally, to tackle H1N1 pandemic would positively impact the market growth. Health institution such as World Health Organization (WHO) have been instrumental in developing vaccines and supporting efficient distribution of the vaccine. After 2009 pandemic of H1N1 influenza, the U.S. government initiated US$ 3 billion H1N1 vaccine project under which it contracted five major companies to develop vaccine for H1N1 influenza. Under the WHO’s Global Influenza Surveillance and Response System, National Influenza Centers and WHO Collaborating Centers are continuously monitoring the influenza viruses circulating in humans and updates the composition of influenza vaccines twice a year.

Furthermore, rising geriatric population worldwide would be another impetus for growth of the H1N1 vaccine market. Global population is crossing the age of 60 at annual rate of 3% according to 2017 UN report. Increased age, maximizes the risk of various respiratory tract related diseases and immune deficient diseases, thereby the risk for infection due to H1N1 virus rises. Awareness amongst patients about preventive healthcare approaches such as vaccination may lead to higher demand for H1N1 vaccines during forecast period.

However, seasonal nature of occurrence of H1N1 flu has led to meagre revenue for many of the key players. For instance, India-based Serum Institute, which produces intranasal live vaccine to treat swine flu had to destroy stock of 2 million doses in the year 2011 due to lack of demand. In contrast, if pandemic arises suddenly, supply of vaccine may be delayed due to slow production of vaccine, which may negatively affect health of many patients. Due to constant evolving nature of H1N1 virus, vaccine may prove to be ineffective in some parts of the world, which may deter the use of vaccines.

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Key Vendors:

Medimmune, AstraZeneca, GlaxoSmithKline, Novartis, Serum Institute of India, Abbott Healthcare, Sanofi Pasture, CSL Biotherapeutics, Sinovac, ID Biomedical Corporation, Cadila Healthcare, and Lupin Ltd.

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Angioplasty balloon is a medical device that is used for surgical widening or unblocking of a blood vessel, especially a coronary artery. A noticeable increase in health conditions have been is observed due to some factors that cause heart related diseases such as obesity, poor diet, and extra cholesterol. .Coronary artery disease is a life threatening disease which occurs due to insufficient supply of blood to the heart, leading to cardiac arrest. Thus, a person experiencing such medical condition should be treated with angioplasty procedure, which cleans the narrow and blocked blood veins. Angioplasty includes insertion of a small balloon tipped catheter into the blood vessel, which is then inflated at the site of blockage to help open the narrowed arteries.

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According to the health protection agency survey 2016, around 610,000 people die every year in the U.S. due to heart defects and this number is still on an upsurge. According to World Health Organizations (WHO) 2011, around 8 million individuals suffering from peripheral artery disease were recorded in the U.S. Coronary heart disease is a major cause of all the deaths in the country, which accounted for around 45% of total deaths. The prevalence of these diseases are expected to increase over the forecast period.

Moreover, the growing ageing population experiencing heart ailments and diabetes, is expected to create higher demand angioplasty balloon catheters over the forecast period.

Increasing number of cardiovascular disease such as peripheral disease, coronary heart disease, and diabetes increase the global market value of angioplasty balloon. However, increase in number of key players of angioplasty balloon market has resulted in price conflicts, which is expected to curb growth of the global market.

Rise in the demand for angioplasty balloon in North America, makes it a global leader.

According to world health organizations (WHO) 2014, the North America angioplasty balloon market is predicted to reach 38% of global market share during next decade. According to the same reports, around 3.4 million people in North America are suffering from cardiovascular diseases. The growing healthcare facilities involving angioplasty in this region, have contributed to market growth. Moreover, the North American region is also a center of technological advancements and inventions of new products for catheters and angioplasty balloon, which further helps boost the market for angioplasty balloon. This makes North America a global leader of angioplasty balloon market.

According to the World Health Organizations reports (WHO) 2016, European region was the second leading global market for angioplasty balloon usage, due to the presence of large geriatric population suffering from cardiovascular diseases in the region. However, Asia Pacific region is expected to lead and emerge as the leading global user for angioplasty balloon over the forecast period. This is due to the world’s largest population present in this region with a noticeable number of people suffering from heart diseases. The costs of angioplasty balloon has decreased by around 40% in over recent decade in India, Japan, and China, which is significantly indicates growth of the angioplasty balloon market in Asia-Pacific.

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Key Vendors:

NATEC Medical, Cook Medical, Medtronic plc, C.R. Bard Inc., Boston Scientific Corporation, Spectranetics Corporation, ENDOCOR GmbH, BIOTRONIK SE & CO. KG, Cordis Corporation, Abbott Laboratories, and Opto Circuits Ltd..

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Renal denervation is a catheter-based minimally invasive procedure. It is a therapy carried out by radiofrequency or ultrasound ablation for uncontrolled hypertension. Renal denervation is performed through endovascular catheter-based procedure to treat hypertension, which is beyond medication control. The procedure consists of a catheter that emits radiofrequency energy across multiple electrodes.

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Radiofrequency pulse is applied to the renal artery, which causes the wall of artery to ablate, reducing the nerve activity, thereby reducing blood pressure. The progress of catheter-based interventional therapies has yielded impressive results in certifying enhanced blood pressure control in patients with complaints of uncontrolled hypertension, vascular, and cardiovascular diseases.

According to the International Journal of Hypertension in 2013, atrial hypertension affects around 24.8% of the global population, posing morbidity and mortality. Rising prevalence of hypertension with inefficient anti-hypertensive medicines, lasting effect of renal denervation, and fast development of renal denervation devices are expected to drive the growth of renal denervation devices market.

The market is expected to grow drastically with the FDA approval of Symplicity HTN-4 renal denervation device, owing to its targeted radiofrequency energy delivery, thereby minimizing the potential threat to surrounding tissues. The market for renal denervation devices and associated processes is also driven by advantages such as higher safety, reduced treatment time, permanent effect, and rising incidence of  uncontrolled & treatment-resistant hypertension.

Regional segmentation of the global renal denervation devices market by Coherent Market Insights comprises North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. The renal denervation devices market in Europe is considered to be the biggest, owing to the increasing number of drug-resistant hypertension cases and technological advances for manufacturing efficient devices. According to the American Heart Association estimates in 2013, around 33% (nearly 70 million people) of the U.S. adult population suffer from high blood pressure. The rising occurrence of uncontrolled hypertension and increasing FDA approvals for drugs are expected to be the major factors driving market growth in North America in the forecast period.

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Key Vendors:

Medtronic Plc., St. Jude Medical, ReCor Medical Inc., Boston Scientific Corporation, and Cardiosonic Ltd.

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Novel Drug Delivery System (NDDS) refers to the formulations, systems to transport pharmaceutical compound in the body, and approaches needed to achieve the desired therapeutic effect. The side effects and slow processing of conventional drug therapy are contributing to the emergence of novel drug delivery system’s concept. Novel ideas based on interdisciplinary approaches controlling the pharmacodynamics, immunogenicity, pharmacokinetics, bio-recognition, and efficiency of drugs were generated. This new system helps in reducing the drug degradation, increasing availability of drugs, and prevent from harmful side effects of drugs. This system provides various commercial and therapeutic benefits by enabling to formulate the novel drug delivery devices so that it can incorporate the drug molecules into the new delivery system.

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Growing prevalence of chronic diseases, drug innovation, and the rising biologics market is also contributing to the growth of novel drug delivery systems market. According to data published by Fraser Institute Canada in July 2016, around 22% of overall sales of pharmaceutical firms in 2013 and expected to reach 32% by 2023 globally. The global spending on biologics has increased by 7% as compared to previous year.

Effectiveness of novel drug delivery system in cancer therapy is also a major factor propelling the novel drug delivery systems market growth. For instance, according to the data published by International Journal of Pharma Sciences and Research (IJPSR), around 9 million deaths occurred due to cancer in 2015 and estimations reveal that around 11.4 million people are expected to die due to cancer by 2030. However, patent cliff, patent expiry, and an increase in injury cases are the factors hindering the growth of global novel drug delivery systems market.

Regional segmentation of novel drug delivery system (NDDS) market by Coherent Market Insights comprises of North America, Latin America, Europe, Asia Pacific, the Middle East, and Africa. North America holds the major share in the novel drug delivery systems market owing to the factors such as growing research and development in the field of drug delivery systems, the high adoption rate of new technology, and supportive reimbursement policies. According to Pharmaceutical Research and Manufacturers of America (PhRMA), the members of PhRMA have invested an estimated amount of $51.2 billion in 2014 in research and development of novel medicines. Asia Pacific is also expected to witness growth in the novel drug delivery systems market due to the increase in investment in pharmaceutical and biotechnology Industry and growing research and development in the healthcare sector.

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Key Vendors:

Abbott Laboratories Limited, Johnson & Johnson, 3M Company, Bayer AG, Novartis AG, Teva Pharmaceuticals Industries Limited, Boston Scientific, AstraZeneca Plc., Sanofi SA, and Genzyme Co..

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The implantable medical devices are man-made devices that are placed inside or on the surface of the body to replace a missing biological structure or to support a damaged biological structure and to enhance an existing biological structure. The implantable medical devices are helping many patients to improve their quality of life through surgical procedures. The implants can be used in different body parts for numerous applications such as pacemakers, orthopedics, cardiovascular stents, neural prosthetics or drug delivery system, and defibrillators.. The surface of implantable medical devices is made up of biomedical materials such as titanium, silicone, or some other material depending upon the desired compatibility and application. Implantable medical devices can be removed when they are no longer needed or they can be placed permanently.

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New technology in the implantable medical devices with various benefits is the major factor driving the growth of the market. For instance, novel technology of patient specific implants using 3D technology and sculptural CAD, have numerous benefits over off-the-implants. Development of next generation devices, upsurge in regulatory approval for clinical trials, rise in neurological disorders in geriatric population, and improved clinical outcome are some of the other important factors that is helping in fuelling the growth of implantable medical devices market.

The demand of implantable medical devices also increasing due to lack of alternative treatments for many severe disorders and injuries. The ability of implantable medical devices to reduce the treatment cost for many chronic disorders is expected to enhance the growth of implantable medical devices market.  However, the implantable medical devices market restraints due to the price pressure from insurance providers and government as they have tighten control over implantation costs.

Regional segmentation of implantable medical devices market by Coherent Market Insights comprises of North America, Latin America, Europe, Asia Pacific, Africa, and Middle East. North America dominates in the implantable medical devices market owing to the factors such as strong healthcare infrastructure, supportive reimbursement, rising geriatric population, awareness about medical assistance, technological advancements, and high purchasing power. Lack of alternative treatments for many chronic disorders and injuries are also helping the growth of implantable medical devices market in North America.  Increase in investment by government for healthcare sector, unmet medical needs, huge population base, are the major factors that might fuel the growth of the implantable medical devices market in Asia-Pacific.

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Key Vendors:

Abbott Laboratories, Boston scientific Corporation, Johnson & Johnson, Dentsply Sirona, Medtronic plc, Smith & Nephew plc, Stryker Corporation, Terumo Corporation, and Zimmer Biomet Holdings.

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Healthcare workers are exposed to infected liquid droplets and aerosols that possess the risk of transmitting diseases such as hospital acquired infections (HSIs) and surgical site infections (SSIs). To avoid susceptibility of such contamination, healthcare workers use surgical face masks, gloves, gowns, caps, and shoe covers, which are produced by fabric foaming technology such as woven, non-woven and knitted. Non-woven surgical fabrics have been adopted by most hospitals, as they are disposable in nature.

Click To Continue Reading on Medical Non-woven Disposables Market

Such materials have been developed due to advancements in technology over the recent past.  Non-woven fabric forming technology is less costly than woven and knitted technology. The materials used for non-woven sheets include polypropylene, polyester, polycarbonate, polyethylene, and polystyrene. The filtration process of non-woven fabrics has various advantages over woven and knitted fabrics such as  its higher bacterial filtration efficiency, higher air permeability, no yarn slippage, lesser contamination risk , and lower manufacturing cost.

Non-woven disposable products offers opportunities for favorable growth of the medical non-woven disposables market. Over the past decades, demand for polymeric nanofibers has tremendously increased, owing to its very large surface area to volume ratio. This exceptional property is suitable for application in medical textile products such as drug delivery systems, surgical face masks, and wound dressing.

Demand for technology offering high absorbent capacity and antimicrobial properties to help reduce chances of cross-contamination, is increasing in the manufacturing of non-woven fabrics. Microencapsulation technology offers immense opportunities to improve properties of medical textile. Suspension of microcapsule is formulated in the development of non-woven textile with prolonged antimicrobial activity.  The textile is then impregnated with microcapsules that are pressure-sensitive, which release the active ingredient upon pressure.

Momentive performance material, in 2011, launched NuWet 550 Hydrophilic silicone finish for non-woven medical disposables, it gives a long-lasting hydrophilic finish to non-woven fabrics such as diapers, surgical wipes. Silicone finish is employed in the medical industry help minimize the migration of water to unwanted areas during surgical processes.

Furthermore, CDC and the Association of State and Territorial Health Officials (ASTHO) have collaborated since July 2010, to ensure funding for basic elements of HAI program infrastructure at the federal, state, and local levels. Growing geriatric population has increased the demand for medical non-woven disposables, in turn, boosting growth of the market. Growing awareness regarding improved hygienic habits among the populace and introduction of new products in the incontinence segment are expected to fuel grow of the medical non-woven disposables market in the near future. High demand for surgical products in developed countries, has fueled growth of the incontinence and surgical product segments, in turn creating immense opportunities for growth of the global medical non-woven disposables market.

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Key Vendors:

Kimberly-Clark Corporation, Medline Industries, Inc., Paul Hartmann AG, Mölnlycke Health Care, Ahlstrom Corporation, Asahi Kasei Corporation, Medtronic, Inc., Svenska Cellulosa, Freudenberg & Co. KG, Aktiebolaget SCA, and Domtar Corporation.

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According to National Institute of Health (NIH), there were approximately 23.5 million American’s suffering from an autoimmune disease in 2012. Moreover, Department of Health and Human Services, in 2017, reported that autoimmune disease (AID) is ranked first in the top ten list of popular health topics. Autoimmune disease has a severe impact on a health, which may lead to various complications in different part of the body, such as heart, brain, kidneys, glands, and nerves. Increasing rate of autoimmune disease is mainly due to genetic and environmental factors, which include dietary components, toxic chemical, and infections.

Click To Continue Reading on Autoimmune Disease Treatment Market

Autoimmune diseases include inflammatory bowel diseases (IBD), rheumatic arthritis (RA), multiple sclerosis (MS), celiac disease (CD), hepatitis, autoimmune thyroiditis (AT), systemic lupus erythematous (SLE) and type 1 diabetes (IDDM).  According to International Journal of Celiac Disease, in 2015, stated that the environmental factors are strongly related to cause autoimmune diseases, which include infections, ecology, and nutrition.

Diagnosis of AID is challenging due to lack of basic knowledge about disease pattern, to identify treatments, and design clinical trials. Increasing awareness among the population about autoimmune diseases and its complications is expected to contribute towards the growth of autoimmune disease treatment market.

Innovation in the treatment of AID is expected to augment the autoimmune disease treatment market. For instance, researchers at the Perelman School of Medicine in 2016, found a way to target a specific subset of antibody, which is responsible for the activation of pemphigus vulgaris (PV) autoimmune disease. The researchers designed chimeric autoantibody receptor therapy (CAART) that can be used to treat this disease without harming the healthy immune system.

Moreover, researchers at the Cumming School of Medicine in 2016, developed a new class of Nano-medicine to treat diseases, specifically type 1 diabetes, multiple sclerosis, and rheumatoid arthritis without compromising immunity. This Nano-medicine is currently being developed at Parvus Therapeutics, Inc., and is funded by Innovate Calgary.

According to the American Autoimmune Related Diseases Association (AARDA), in 2017, approximately 50 million Americans are suffering from autoimmune disease. High prevalence of autoimmune diseases demands for new treatment approach, which may include biomarkers, stem cell research, and genetic research. Biological agents such as TNF agents, monoclonal antibodies, tissue and organ engineering procedure, gene-based delivery system, modulators of the immune system, and cell-based treatments are under evaluation for the treatment of AID in near future.

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Key Vendors:

Johnson & Johnson, Abbott Laboratories, F. Hoffmann-La Roche Ltd., Active Biotech, GlaxoSmithKline plc, Eli Lilly and Company, AutoImmune Inc., Pfizer, Inc. AstraZeneca plc, Lupin Limited, 4SC AG, Amgen, Inc., and Bristol-Myers Squibb.

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Wearable sensors are the devices that collect information about biological and physical properties of body and environment by the sensors present in wearable devices. This information is utilized further to measure the output information of body. Sensors are implemented in wearable devices to track environmental activities, such as temperature and weather information and to track fitness and health activities, such as body temperature, heart rate, stress level, heart pressure, blood pressure, movements, speed, and local temperature. Wearable sensors are used in devices, such as a smart-watch, smart shoes, body-wear, fitness watch, glasses, virtual reality headsets, sleep masks, and jewelry.

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The sensors device processes according to the surrounding environment and it is implemented on the wearable device to monitor body activities, which include, heart rate, body temperature, and blood pressure. Wearable sensors market is expected to show a significant growth over the forecast period, owing to the demand for wearable sensor devices in various applications such as healthcare, lifestyle, fitness, and security. Moreover, recent advancements in telecommunication, data analysis, sensor manufacturing, and microelectronics are providing opportunities for adoption of wearable sensors in the digital health environment.

Additionally, in the healthcare industry, wearable sensors are used for monitoring patient’s conditions. These devices are also used in sports, military, and entertainment. For instance, Apple watch is a wearable device, which includes microphone, accelerometer, and a pulse sensor. Wearable sensors are integrated into garments, watches, eye-glasses, and smartphones, which is fueling the growth of the wearable sensor market.

Decreasing cost, attractive accessories, and integration with consumer electronic devices are the key factors for boosting the growth of global wearable device market. Additionally, introduction of key players in market such as Google, Amazon, Facebook, Apple, Microsoft, smartphone penetration in sensor technology, the high occurrence of chronic disease related to blood pressure and heart rate, geriatric population with cardiac and neurological disorders, fitness awareness, and reduced digital health-cost are anticipated to significantly drive the growth of global wearable sensors market.

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Key Vendors:

Google, Panasonic Corporation, Freescale Semiconductor, Fossil Groups, InvenSense, Facebook, Amazon, Apple, Microsoft, Infineon Technologies AG, ST Microelectronics, and Analog Devices, Inc.

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Muscular Dystrophy is characterized by a collection of muscle-wasting conditions. The disorder is caused by genetic mutations which interfere with the production of muscle protein dystrophin, necessary to build muscles. Muscular dystrophy is a genetic disease, consequently, the chance of an individual developing a disease increases with a history of muscular dystrophy in the family. The symptoms include shortening of muscles and tendons, the curvature of spine, weakening of heart muscles leading to cardiac problems, and breathing problems.

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The most common forms of muscular dystrophies include duchenne muscular dystrophy, becker muscular dystrophy, myotonic disease, congenital disease and oculopharyngeal muscular dystrophy. The cure for any form of muscular dystrophy is currently unspecified, but the symptoms can be relived through physical therapy, exercise, rehabilitative devices like a powered wheelchair, respiratory care and surgery.

According to the research conducted by the Karger Journal on 2014, the global prevalence for muscular dystrophies accounted between 19.8 and 25.1 per 100,000 person every year with myotonic dystrophy (0.5-18.1 per 100,000), duchenne muscular dystrophy (1.7-4.2) and facioscapulohumeral muscular dystrophy (3.2-4.6 per 100,000) to be the most common types of disorders.

The initial research phase of the therapies and ongoing clinical trials for the development of innovative products drives the global muscular dystrophy treatment market. Also, specific guidance for drug development for muscular dystrophy drugs published by the U.S. FDA in 2015 is expected to accelerate the new drug development for the treatment of a disorder. The emergence of disease-modifying therapies as a replacement for the unmet medical needs of patients who are not amenable to mutation-specific drugs is likely expected to fuel the revenue of the global muscular dystrophy treatment market in the forecast period. However, the fast prognosis of a disorder and low treatment seeking rate due to delayed diagnosis are the major limiting factors for the growth of global muscular dystrophy treatment market.

North America is expected to dominate the global muscular dystrophy treatment market owing to the absence of marketed pharmacological therapies indicated to treat muscular dystrophy, rising prevalence of the disease and rising research and development for producing effective drugs. Europe is expected to boost the market share in the forecast period with the growing public awareness and increasing research activities.

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Key Vendors:

Santhera Pharmaceuticals, PTC Therapeutics, BioMarin Pharmaceutical, Sarepta Therapeutics and Eli Lilly.

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Snoring is the vibration of respiratory structures which results in sound while sleeping. It is a sleeping disorder caused due to monotonous narrowing and collapsing of the upper airway. Snoring have various adverse effects on health include coronary artery disease, systemic hypertension, atrial fibrillation, and stroke. Snoring is one of the factors of sleep deprivation, which may be further caused due to throat weakness, mispositioned jaw, obesity, and obstruction in the nasal passageway due to intake of alcohol and drugs.

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Snoring is a general phenomenon which can be treated or cured by use of anti-snoring devices or by nasal surgery. More than 300 devices are registered in the U.S. Patent and Trademark Office to cure snoring. However, surgery for the treatment of snoring include Laser-assisted uvulopalatoplasty, Uvulopalatopharyngoplasty, Radiofrequency ablation, sclerotherapy, Pillar procedure and others.

According to World Drug Report 2016, drug intake has reached epidemic levels with around 247 million drug users worldwide. Snoring is mainly caused due to intake of alcohol and drugs, which relax throat muscles. Moreover, increased consumption of alcohol by an individual for over a period of time causes respiratory tract blockage and also obesity is a major concern, leading to soring. According to World Health Organization (WHO), in 2014, around 1.9 billion adults were reported to have overweight, from which over 600 million adults were obese.

Obesity is the second most common factor which results in snoring, it causes accumulation of fat around throat which causes increase in the prevalence of respiratory tract blockage. The removal of fat can be obtained by the laser-assisted surgeries, which in turn is expected to augment the market growth in the near future. Lack of knowledge about proper treatment and high cost of anti-snoring devices and surgeries are some of the factors restraining the anti-snoring treatment market growth.

Regional segmentation of the anti-snoring treatment market by Coherent Market Insights comprises North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold the dominant position in the anti-snoring treatment market, due to the increasing prevalence of snoring disorder in region. According to American Sleep Foundation, in 2017, around 90 million American of all age group and genders are affected from one or the other respiratory disorder leading to snoring leading to increasing prevalence of snoring, expected to increase the demand for its treatment and hence fueling anti-snoring treatment market.

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Key Vendors:

GlaxoSmithKline, plc, Apnea Sciences Corporation, Fisher & Paykel Healthcare, Sleeping Well, LLC, Sleep Well Enjoy Life, Ltd., AccuMED Corp., ResMed, Inc., and Airing CPAP. 

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Targeted cancer therapies are drugs which block the growth and proliferation of cancer by interfering with specific molecules such as DNA or proteins, which are involved in the growth or expansion of cancerous cells. Targeted cancer therapies differ in several ways from standard chemotherapy. Standard chemotherapy act on all rapidly dividing cancerous cells as well as normal cells, while targeted cancer therapies act on specific molecular targets that are associated with cancer. Standard chemotherapy agents are cytotoxic that kill tumor cells, while targeted therapies are often cytostatic that blocks tumor cell proliferation.

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Targeted therapies uses information about a person’s gene and protein to prevent, diagnose, and treat disease, which makes them extremely applicable in the making of precision medicine. Targeted therapy drugs are mainly used for the treatment of cancer, and are mostly used along with another treatments such as chemotherapy, surgery, and radiation therapy.

Targeted cancer therapies market is growing due to the increasing incidences of cancers such as breast cancer, lung cancer, colorectal cancer, gastrointestinal cancer and among others. According to the National Cancer Institute, in 2016, around 1,685,210 new cases of cancer were diagnosed in U.S. and 5,95,690 people died from the disease. However, increasing cancer research funding, rising insurance coverage and increase in number of new targeted anti-cancer drugs supports the revenue growth of targeted cancer therapies market.

According to the American Institute of Cancer Research (AICR), in U.S., cancer treatment costs more than any other disease, accounted for around US$ 895 billion a year. According to the study published in the Journal of Clinical Oncology, in 2015, targeted therapies accounted for 63% of the all chemotherapy expenditures in the U.S. in 2011. This further propels the targeted cancer therapies market in the near future. Targeted therapy drugs are very expensive, costs more than US$ 14,000 per patient in the initial stage of treatment. Rising cost of targeted oral anticancer medicines is a major factor in rising overall cost of targeted cancer therapies.

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Key Vendors:

Abbott Laboratories, Bayer AG, Boehringer Ingelheim GmbH, GlaxoSmithKline plc, AstraZeneca PLC, OncoGenex Pharmaceuticals Inc., Pfizer, Inc., AVEO Pharmaceuticals Inc., and CYTOKINETICS INC.

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Laboratory equipment includes important aspects in healthcare, medical and pharmaceutical research study. These equipment are getting smaller and smaller as new technologies are eliminating these equipment like series of pumps and valves which are required to store samples. New technologies includes recent advancements in fluidic components which are capable of integrating multiple laboratory functions into a single chip requiring smaller amounts of samples.

Government and private research firms are taking initiatives in the research and development activities in context to diagnose and treat several disease worldwide through innovative technologies like specialty instruments. For instance, in 2016, Cancer Research UK spend US$ 583 million on cancer research to develop new treatment and to optimize existing cancer treatment. The amount spent was US$ 51 million on clinical trials study, US$ 50 million on research into new drugs and US$ 23 million on research to identify possible causes of cancer.

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Increasing chronic diseases such as chronic respiratory diseases, cardiovascular diseases and diabetes, and increasing incidence of lifestyle diseases such as heart disease, obesity, atherosclerosis and hereditary disease such as haemophilia, Down’s syndrome, cystic fibrosis and sickle cell anemia are leading to the increasing demand of laboratory equipment to bring innovative technologies in the market. According to World Health Organization (WHO), noncommunicable disease leads to cause 40 million deaths each year, which is equivalent to 70% of all deaths worldwide. Cardiovascular diseases account for most of NCD mortality (17.7 million) annually, followed by cancer (8.8 million), respiratory disease (3.9 million) and diabetes (1.6 million).

For instance, in March 2017, Echo—a San Diego-based company—unveiled the Revolve hybrid microscope, a digital, all-in-one microscope. The innovative microscope integrates the features of upright microscope and an inverted microscope. It is used primarily in clinical laboratories and by cancer and stem cell scientists to capture high resolution images and it also provides cloud storage to allow the remotely maintain, manage and backed up images taken by the microscope. The company received the US$ 7.5 million funding from two capital ventures, moreover the funding helps to increase the production of Revolve hybrid microscope.

In October 2017, Beckman Coulter, Inc. introduced next generation, refrigerated, high-speed benchtop centrifuge-Avanti J-15 Series. It allows to improve operational efficiency and saves time by shortening workflows. These technology and product advancements helps to boost the laboratory equipment market in future.

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Key Vendors:

Thermo Fisher Scientific, Inc., Merck KGaA, Beckman Coulter, Inc., Danaher Corporation, Shimadzu Corporation, PerkinElmer, Inc. and Agilent Technologies.

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The global cardiovascular drug market is primarily driven by increase in prevalence of heart diseases coupled with rising geriatric population and lifestyle related diseases. In order to cater to this increasing population suffering from cardiovascular diseases, drugs for treatment and prevention for these diseases is required. Rising number of diabetic patients is also expected to be another factor for growth of the global cardiovascular drugs market. According American Diabetes Association, in 2015, 30.3 Americans had diabetes, which is 9.4% of the total U.S population.

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Some of the common cardiovascular diseases include hypertensive heart disease, rheumatic heart disease, ischemic heart disease, inflammatory heart disease, and cerebrovascular heart disease. Major problems associated with hypertensive heart disease include angina, hypertrophy, and heart failure. These problems are caused due to high blood pressure in the heart’s arteries and muscles, which causes narrowing of arteries and thickening and enlargement of heart.

Manufacturers in the market are focusing on mergers and acquisition and new product launches, which is positively affecting the market growth. However, stringent drug approval process and side effects of some cardiovascular drugs hamper growth of the global cardiovascular drugs market. Moreover, the patent expiry of various blockbuster drugs is also expected to adversely affect revenue growth of the global cardiovascular drugs market.

According to American Heart Association (AHA), in 2013, cardiovascular diseases accounted for over 17.3 million deaths globally, representing 31% of all global deaths. The global number is expected to rise to 23.6 million by 2030. In 2010, the global burden of cardiovascular diseases was US$ 863 billion, and it is expected to rise to US$1044 billion by 2030. Around 2,200 U.S. citizens die due to cardiovascular diseases, everyday, which is one death in every 40 seconds. Moreover, coronary heart disease accounts for (45.1%) of the total cardiovascular disease, followed by stroke (16.5%), high blood pressure (9.1%), heart failure (8.5%), diseases related to arteries (3.2%), and other cardiovascular diseases in the U.S.

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Key Vendors:

Pfizer Inc., Bayer AG., Novartis AG., Merck and Co. Inc., AstraZeneca Plc, Bristol Myers Squibb Company, Abbott Laboratories, Sun Pharma Industries, Gilead Sciences Inc., Otsuka Holdings Co., Ltd. Takeda Pharmaceutical Company Ltd, Eli Lilly and Company, and Johnson & Johnson.

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